Do exosomes contain growth factors?

Discover how growth factors improve skin care by providing vital instructions to skin cells and increasing collagen and elastin for greater firmness. Growth factors focus on specific actions, while exosomes offer complete signs of repair. For people over 35, growth factor serums help compensate for collagen loss and sun damage. Recommended serums include SkinMedica TNS and Plated Intense, known as for its effectiveness.

Select products with strong clinical support and look for “growth factor” on labels. Apply the serums to clean skin, allowing them to absorb before continuing with other products. They are found in all mammalian cells and are small, nano-sized extracellular bubbles or vesicles that are released from cells. Exosomes contain proteins, growth factors, and genetic information, such as RNA, microRNA and DNA, which are important in helping one cell communicate with another and promoting healing.

They have become a hot topic in regenerative medicine in recent years and are also being hailed as the next major breakthrough in hair and skin care. Exosomes are secreted by stem cells and carry growth factors, RNA, and other cellular signals. Exosomes protect growth factors and deliver them directly to target cells. Exosomes derived from mesenchymal stem cells have received significant attention in the field of care for skin due to its regenerative properties.

These exosomes contain different types of proteins and growth factors that can stimulate collagen production, reduce inflammation and improve overall skin health. By harnessing the regenerative potential of mesenchymal stem cell-derived exosomes, skin care products can effectively treat several signs of aging and promote a more youthful appearance. In this video, I discuss exosomes and skin aging with a regenerative medicine dermatologist and a transplant cardiologist, who have done a lot of research on the rejuvenating effects of exosomes. There is growing evidence to suggest that stem cell-derived exosomes could represent a new cell-free therapy with compelling advantages over MSCs original, such as the absence of the risk of tumor formation and lower immunogenicity.

Exosomal miRNAs can affect many aspects of the physiological and pathological conditions of HCC and indicate that exosomal miRNAs can not only serve as sensitive biomarkers for the diagnosis and recurrence of cancer, but can also be used as therapeutic agents to attack the progression of HCC. It's also worth noting that the exosomes used by aesthetic professionals are derived from human sources (usually mesenchymal stem cells from the umbilical cord, amniotic fluid, or placenta), while over-the-counter formulas use human, plant, or laboratory exosomes. Exosome therapy, which is often administered through topical applications or injections, is generally considered less invasive and more convenient than PRP, which requires a blood draw and centrifugation to separate platelets.